HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl pyrazolidine-1-carboxylate → t-Butyl 2-[(5-(4-chlorophenyl)-6-(2,2,2-trifluoroethoxy)-3-pyridinyl)carbonyl]-pyrazolidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl pyrazolidine-1-carboxylate | HCID 21857793 | — |
| Reactant | 5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid | HCID 66686971 | — |
| Product | t-Butyl 2-[(5-(4-chlorophenyl)-6-(2,2,2-trifluoroethoxy)-3-pyridinyl)carbonyl]-pyrazolidine-1-carboxylate | HCID 71294447 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1 using 5-(4-chlorophenyl)-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid (CAN 1018782-82-5) and 1-pyrazolidinecarboxylic acid 1,1-dimethylethyl ester (CAN 57699-91-9) as starting materials; MS (EI) 486.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08648099B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-13ad7180d565474e85d2285da3b37b3a |
| Source note | uspto-grants-2014_02 |