참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| 반응물 | 4,5-Diaminopyrimidine | HCID 83703 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 7H-Purin-8-ol | HCID 229771 | 567.7% |
반응 단계
Pyrimidine-4,5-diamine (1.1 g, 10 mmol) and 1,1′-carbonyl diimidazole 1.78 g, 1.1 mmol) were added to dioxane (15 mL) and the reaction mixture was stirred at 90° C. for 48 hours. The mixture was cooled and the precipitate was recovered by filtration, rinsed with cold dioxane, and dried to give 850 mg (61%) of 7,9-dihydro-purin-8-one.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08809402B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_08 |
|---|
| ORD ID | ord-0ba2525ed6324bc6b28225dea4d0f0b5 |
|---|
| 출처 메모 | uspto-grants-2014_08 |
|---|
