HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Cyclopent-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane → 5-Cyclopent-1-enyl-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid methylester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Cyclopent-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 15486611 | — |
| Reactant | Methyl 5-bromo-6-(2,2,2-trifluoroethoxy)nicotinate | HCID 66686828 | — |
| Product | 5-Cyclopent-1-enyl-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid methylester | HCID 71293985 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 12a using 5-bromo-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid methyl ester (CAN 1211589-51-3) and 2-(1-cyclopenten-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAN 287944-10-9) as starting materials; MS (EI) 302.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08648099B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-a27a734bc7014049b1e3ade82db9f9cd |
| Source note | uspto-grants-2014_02 |