HCID 11235538, compound → HCID 66780680, compound

HRID 2407035Notes

Reaction equation

HRID 2407035 reaction equation
[Na:1].N1C(N)=C2C(N(C([C@@H]([C@H](CO)OCP(O)(O)=O)O)=O)C=N2)=NC=1.[N:25]1([C:34]([C@@H:36]([C@H:38]([CH2:51][OH:52])[O:39][CH2:40][P:41]([O:47]C(C)C)([O:43]C(C)C)=[O:42])[OH:37])=[O:35])[CH:33]=[C:31]([CH3:32])[C:29](=[O:30])[NH:28][C:26]1=[O:27]>>[Na:1].[N:25]1([C:34]([C@@H:36]([C@H:38]([CH2:51][OH:52])[O:39][CH2:40][P:41]([OH:43])([OH:47])=[O:42])[OH:37])=[O:35])[CH:33]=[C:31]([CH3:32])[C:29](=[O:30])[NH:28][C:26]1=[O:27]

Participants

3

Reactant 2

HCID 11235538HCID 11235538, compoundHCID 66781133HCID 66781133, compound

Product 1

HCID 66780680HCID 66780680, compoundYield 42%

Procedure

This compound was prepared as described for 3a, using 16 (220 mg, 0.58 mmol) as starting material. Compound 3b (90 mg, 0.24 mmol) was obtained as a colorless solid in 42% yield, which was characterized as follows:

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-41fb47296f0b47c18606a50ac7536d36
Source dataset
uspto-grants-2014_08
Patent number
US08809520B2

Reaction notes

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