HCID 11350531, compound → HCID 178507177, compound

HRID 2407038Notes

Reaction equation

HRID 2407038 reaction equation
[Na:1].[N:2]1[C:10]([NH2:11])=[C:9]2[C:5]([N:6](C([C@@H]([C@H](CO)OCP(O)(O)=O)O)=O)[CH:7]=[N:8]2)=[N:4][CH:3]=1.N1C(N)=C2C(N([C:35]([CH2:37][C@H:38]([CH2:51][OH:52])[O:39][CH2:40][P:41]([O:47]C(C)C)([O:43]C(C)C)=[O:42])=[O:36])C=N2)=NC=1>>[Na:1].[N:2]1([C:35]([CH2:37][C@H:38]([CH2:51][OH:52])[O:39][CH2:40][P:41]([OH:43])([OH:47])=[O:42])=[O:36])[C:10]([NH2:11])=[C:9]2[C:5](=[N:6][CH:7]=[N:8]2)[N:4]=[CH:3]1

Participants

3

Reactant 2

HCID 11350531HCID 11350531, compoundHCID 66781133HCID 66781133, compound

Product 1

HCID 178507177HCID 178507177, compoundYield 43%

Procedure

This compound was prepared as described for 3a, using 19 (70 mg, 0.23 mmol) as a starting material. Compound 3e (38 mg, 0.11 mmol) was obtained as a colorless solid, in 43% yield, which was characterized as follows:

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-538f6d40319f4f69a0d22836393f603e
Source dataset
uspto-grants-2014_08
Patent number
US08809520B2

Reaction notes

Loading…