HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Aminomorpholine → 5-cyclohexyl-N-morpholino-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Aminomorpholine | HCID 20315 | — |
| Reactant | 5-Cyclohexyl-6-(2,2,2-trifluoroethoxy)nicotinic acid | HCID 71293952 | — |
| Product | 5-cyclohexyl-N-morpholino-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxamide | HCID 71294123 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1 using 5-cyclohexyl-6-(2,2,2-trifluoro-ethoxy)-3-pyridinecarboxylic acid (example 12c) and 4-morpholinamine (CAN 4319-49-7) as starting materials; LC-MS (UV peak area/ESI) 99.0%, 388.1849 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08648099B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-123eee9cb1b34176b8e6448fbe480cf5 |
| Source note | uspto-grants-2014_02 |