HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Pyrrolidinamine → 5-cyclohexyl-N-(pyrrolidin-1-yl)-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Pyrrolidinamine | HCID 27946 | — |
| Reactant | 5-Cyclohexyl-6-(2,2,2-trifluoroethoxy)nicotinic acid | HCID 71293952 | — |
| Product | 5-cyclohexyl-N-(pyrrolidin-1-yl)-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxamide | HCID 71294001 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1 using 5-cyclohexyl-6-(2,2,2-trifluoro-ethoxy)-3-pyridinecarboxylic acid (example 12c) and 1-pyrrolidinamine (CAN 16596-41-1) as starting materials; LC-MS (UV peak area/ESI) 100.0%, 372.1899 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08648099B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-93b290fb7a964b32bda99af24fdc684c |
| Source note | uspto-grants-2014_02 |