HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-6-(1-methylhydrazinyl)pyridazine → N'-(6-chloropyridazin-3-yl)-5-cyclohexyl-N'-methyl-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid hydrazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-6-(1-methylhydrazinyl)pyridazine | HCID 2735815 | — |
| Reactant | 5-Cyclohexyl-6-(2,2,2-trifluoroethoxy)nicotinic acid | HCID 71293952 | — |
| Product | N'-(6-chloropyridazin-3-yl)-5-cyclohexyl-N'-methyl-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid hydrazide | HCID 71510018 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1 using 5-cyclohexyl-6-(2,2,2-trifluoro-ethoxy)-3-pyridinecarboxylic acid (example 12c) and 3-chloro-6-(1-methylhydrazinyl)-pyridazine (CAN 76953-33-8) as starting materials; LC-MS (UV peak area/ESI) 100.0%, 444.1408 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08648099B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-c7435d94371f4c3f948f87b282b5308f |
| Source note | uspto-grants-2014_02 |