3,5-Dimethylphenylboronic acid → HCID 53353232, compound

HRID 2407124Notes

Reaction equation

HRID 2407124 reaction equation
Br[C:2]1[N:7]=[N:6][C:5]([NH2:8])=[N:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.[CH3:15][C:16]1[CH:17]=[C:18](B(O)O)[CH:19]=[C:20]([CH3:22])[CH:21]=1>>[CH3:15][C:16]1[CH:17]=[C:18]([C:2]2[N:7]=[N:6][C:5]([NH2:8])=[N:4][C:3]=2[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH:19]=[C:20]([CH3:22])[CH:21]=1

Participants

3

Reactant 2

HCID 27343493,5-Dimethylphenylboronic acidHCID 866761146-Bromo-5-phenyl-1,2,4-triazin-3-amine

Product 1

HCID 53353232HCID 53353232, compoundYield 65.4%

Procedure

6-(3,5-Dimethylphenyl)-5-phenyl-1,2,4-triazin-3-amine (54 mg, 65%) was prepared from 6-bromo-5-phenyl-1,2,4-triazin-3-amine (75 mg, 0.299 mmol) and 3,5-dimethylphenylboronic acid (51.5 mg, 0.344 mmol) according to the general procedure of Example 1.

Sources & evidence

ORD record
ord-4e6e1bb49eea42db9577fd6bed992326
Source dataset
uspto-grants-2014_08
Patent number
US08809525B2

Reaction notes

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