3,3-Dimethylpiperidine → HCID 53354728, compound

HRID 2407145Notes

Reaction equation

HRID 2407145 reaction equation
Br[C:2]1[N:7]=[N:6][C:5]([NH2:8])=[N:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.[CH3:15][C:16]1([CH3:22])[CH2:21][CH2:20][CH2:19][NH:18][CH2:17]1>>[CH3:15][C:16]1([CH3:22])[CH2:21][CH2:20][CH2:19][N:18]([C:2]2[N:7]=[N:6][C:5]([NH2:8])=[N:4][C:3]=2[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH2:17]1

Participants

3

Reactant 2

HCID 709423,3-DimethylpiperidineHCID 866761146-Bromo-5-phenyl-1,2,4-triazin-3-amine

Product 1

HCID 53354728HCID 53354728, compoundYield 10%

Procedure

6-(3,3-Dimethylpiperidin-1-yl)-5-phenyl-1,2,4-triazin-3-amine (54 mg, 10%) was prepared from 6-bromo-5-phenyl-1,2,4-triazin-3-amine (0.50 g, 1.99 mmol) and 3,3-dimethylpiperidine (0.27 g, 2.39 mmol) according to the general procedure of Example 2.

Sources & evidence

ORD record
ord-1c977dbc99fc40f2b515e16ee98bc167
Source dataset
uspto-grants-2014_08
Patent number
US08809525B2

Reaction notes

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