2-Isopropylphenol → HCID 67364903, compound

HRID 2407154Notes

Reaction equation

HRID 2407154 reaction equation
Br[C:2]1[N:7]=[N:6][C:5]([NH2:8])=[N:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.[CH:15]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[OH:24])([CH3:17])[CH3:16]>>[C:9]1([C:3]2[N:4]=[C:5]([NH2:8])[N:6]=[N:7][C:2]=2[O:24][C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=2[CH:15]([CH3:17])[CH3:16])[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 69432-IsopropylphenolHCID 866761146-Bromo-5-phenyl-1,2,4-triazin-3-amine

Product 1

HCID 67364903HCID 67364903, compoundYield 7%

Procedure

5-Phenyl-6-[2-(propan-2-yl)phenoxy]-1,2,4-triazin-3-amine (20 mg, 7%) was prepared from 6-bromo-5-phenyl-1,2,4-triazin-3-amine (0.40 g, 1.59 mmol) and 2-isopropyl phenol (0.43 g, 3.18 mmol) according to the general procedure of Example 3.

Sources & evidence

ORD record
ord-ff5419883cf8452da160b3a92337a4ed
Source dataset
uspto-grants-2014_08
Patent number
US08809525B2

Reaction notes

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