4-Methoxyphenol → HCID 67363222, compound

HRID 2407158Notes

Reaction equation

HRID 2407158 reaction equation
Br[C:2]1[N:7]=[N:6][C:5]([NH2:8])=[N:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.[CH3:15][O:16][C:17]1[CH:22]=[CH:21][C:20]([OH:23])=[CH:19][CH:18]=1>>[CH3:15][O:16][C:17]1[CH:22]=[CH:21][C:20]([O:23][C:2]2[N:7]=[N:6][C:5]([NH2:8])=[N:4][C:3]=2[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 90154-MethoxyphenolHCID 866761146-Bromo-5-phenyl-1,2,4-triazin-3-amine

Product 1

HCID 67363222HCID 67363222, compoundYield 13%

Procedure

6-(4-Methoxyphenoxy)-5-phenyl-1,2,4-triazin-3-amine (45 mg, 13%) was prepared from 6-bromo-5-phenyl-1,2,4-triazin-3-amine (0.30 g, 1.19 mmol) and 4-methoxyphenol (0.30 g, 2.39 mmol) according to the general procedure of Example 3.

Sources & evidence

ORD record
ord-9b08c225212947dba6585c547fe55480
Source dataset
uspto-grants-2014_08
Patent number
US08809525B2

Reaction notes

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