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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2407237Generated: October 30, 2026

Borane;tetrahydrofuran → HCID 25174508, compound

https://huagongshe.com/reaction/2407237

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBorane;tetrahydrofuranHCID 2723981—
ReactantHCID 66727196HCID 66727196—
ProductHCID 25174508HCID 25174508111.4%

Reaction Steps

(R)-2,3-Dihydrobenzo[1,4]dioxin-2-yl-[(R*)-3-(3-fluorophenyl)piperidin-1-yl]methanone (1.21 g, 3.51 mmol) was treated with BH3THF according to the above general procedure. 1.28 g crude product was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08809536B2
Source datasetuspto-grants-2014_08
ORD IDord-44e7d08bacba40dd9e025d4629a29a34
Source noteuspto-grants-2014_08