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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2407243Generated: October 31, 2026

Borane;tetrahydrofuran → HCID 25174840, compound

https://huagongshe.com/reaction/2407243

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBorane;tetrahydrofuranHCID 2723981—
ReactantHCID 66726963HCID 66726963—
ProductHCID 25174840HCID 2517484043.8%

Reaction Steps

(R)-2,3-Dihydrobenzo[1,4]dioxin-2-yl-[(R*)-3-(4-trifluoromethylphenyl)piperidin-1-yl]methanone (18 mg, 0.046 mmol) was treated with BH3THF according to the above general procedure. Flash chromatography gave 7.6 mg of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08809536B2
Source datasetuspto-grants-2014_08
ORD IDord-711cf4cd9dba48e58119ab61f754f7bf
Source noteuspto-grants-2014_08