1-(2,3-Dihydrobenzo[1,4]dioxin-2-ylmethyl)-3-methoxymethyl-3-methylpiperidine → 3-Allyl-1-(2,3-dihydrobenzo[1,4]dioxin-2-ylmethyl)-3-methoxymethylpiperidine

HRID 2407291Notes

Reaction equation

HRID 2407291 reaction equation
[CH2:1]([C:4]1([CH2:21][OH:22])[CH2:9][CH2:8][CH2:7][N:6]([CH2:10][CH:11]2[O:16][C:15]3[CH:17]=[CH:18][CH:19]=[CH:20][C:14]=3[O:13][CH2:12]2)[CH2:5]1)[CH:2]=[CH2:3].O1C2C=CC=CC=2OC[CH:24]1CN1CCCC(COC)(C)C1>>[CH2:1]([C:4]1([CH2:21][O:22][CH3:24])[CH2:9][CH2:8][CH2:7][N:6]([CH2:10][CH:11]2[O:16][C:15]3[CH:17]=[CH:18][CH:19]=[CH:20][C:14]=3[O:13][CH2:12]2)[CH2:5]1)[CH:2]=[CH2:3]

Participants

3

Reactant 2

HCID 251756611-(2,3-Dihydrobenzo[1,4]dioxin-2-ylmethyl)-3-methoxymethyl-3-methylpiperidineHCID 25175824[3-Allyl-1-(2,3-dihydrobenzo[1,4]dioxin-2-ylmethyl)piperidin-3-yl]methanol

Product 1

HCID 251759643-Allyl-1-(2,3-dihydrobenzo[1,4]dioxin-2-ylmethyl)-3-methoxymethylpiperidine

Procedure

Prepared from [3-allyl-1-(2,3-dihydrobenzo[1,4]dioxin-2-ylmethyl)-piperidin-3-yl]methanol using the procedure described for 1-(2,3-dihydrobenzo[1,4]dioxin-2-ylmethyl)-3-methoxymethyl-3-methylpiperidine.

Sources & evidence

ORD record
ord-f778137e17e44b99894dc8d58d169e29
Source dataset
uspto-grants-2014_08
Patent number
US08809536B2

Reaction notes

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