m-Toluidine → HCID 86688159, compound

Participants

Reaction Steps

The compound obtained in Step 1 (1.30 g, 6.53 mmol), m-toluidine (1.40 g, 13.1 mmol), and potassium carbonate (870 mg, 6.53 mmol) were dissolved in acetonitrile, and then stirred under reflux for 12 hours. The solvent was removed by concentration under reduced pressure, and then the precipitate generated by adding hexane thereto was filtered and washed with hexane, to obtain methyl 3-nitro-4-(m-tolylamino)benzoate as an orange solid (1.37 g, 73%).

Provenance & Evidence