Ethyl 3-hydroxybenzoate → HCID 86651082, compound

HRID 2407365Notes

Reaction equation

HRID 2407365 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5](F)=[CH:4][N:3]=1.[OH:9][C:10]1[CH:11]=[C:12]([CH:18]=[CH:19][CH:20]=1)[C:13]([O:15]CC)=[O:14]>>[Br:1][C:2]1[N:3]=[CH:4][C:5]([O:9][C:10]2[CH:11]=[C:12]([CH:18]=[CH:19][CH:20]=2)[C:13]([OH:15])=[O:14])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 24522Ethyl 3-hydroxybenzoateHCID 27831712-Bromo-5-fluoropyridine

Product 1

HCID 86651082HCID 86651082, compound

Procedure

Prepared from 2-bromo-5-fluoropyridine and ethyl 3-hydroxybenzoate. 1H NMR (400 MHz, DMSO-d6) δ 13.12 (br. s., 1H), 8.28 (d, 1H), 7.78 (d, 1H), 7.69 (d, 1H), 7.56 (t, 1H), 7.48-7.54 (m, 2H), 7.39 (dd, 1H)

Sources & evidence

ORD record
ord-4d01267c384e4236be660fb9da615f6e
Source dataset
uspto-grants-2014_08
Patent number
US08809540B2

Reaction notes

Loading…