HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dichlorobenzyl isocyanate → HCID 89523898, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dichlorobenzyl isocyanate | HCID 4612708 | — |
| Reactant | 3,6-Diaza-bicyclo(3.2.0)heptane-6-carboxylic acid tert-butyl ester | HCID 46738181 | — |
| Product | HCID 89523898 | HCID 89523898 | 88% |
Reaction Steps
In analogy to the experimental procedure of example 1a) rac-3,6-diaza-bicyclo[3.2.0]heptane-6-carboxylic acid tert-butyl ester instead of 6-(tert-butoxycarbonyl)-2,6-diaza-spiro[3.3]heptane oxalate was converted using 2,4-dichloro-1-(isocyanatomethyl)benzene into the title compound (691 mg, 88%) which was obtained as a colorless solid. MS (EI) m/e: 400.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08809552B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-54ba7e0bfd724801b9ccaad162e9bca7 |
| Source note | uspto-grants-2014_08 |