Sodium Nitrite → Perfluoro-2-[3-(methoxy)propoxy]acetic acid

Participants

Reaction Steps

70 mL of acetic acid, 0.24 g sodium nitrite, TEMPO (0.18 g), CH3CO2Na (3.69 g) and 5 g of 2,2-difluoro-2-(1,1,2,2,3,3-hexafluoro-3-trifluoromethoxy-propoxy)-ethanol were placed in the reaction vessel described in example 17. The reaction was carried out and worked up as described in example 9. Distillation of the residue gave 4.05 g of the acid (20 mmHg, 65° C.). Yield: 78%.

Provenance & Evidence