Oxalyl chloride → HCID 86659054, compound

Participants

Reaction Steps

Oxalyl chloride (0.24 mL) was added dropwise to a 0° C. solution of the compound prepared in Example 58 (615 mg) in dichloromethane (8 mL). The reaction was stirred at room temperature for 30 minutes and then concentrated to obtain the title compound (600 mg) having the following physical data. 1H NMR (DMSO-d6): δ 7.92-7.81 (m, 2H), 7.62-7.48 (m, 3H), 7.38 (s, 1H), 4.59 (s, 2H), 3.50-3.36 (m, 2H), 3.12-2.97 (m, 2H), 2.22-2.09 (m, 2H), 1.99-1.79 (m, 3H), 1.67-1.50 (m, 2H).

Provenance & Evidence