3-Phenyl-1,2-oxazole-5-carbaldehyde → HCID 58504144, compound

HRID 2407690Notes

Reaction equation

HRID 2407690 reaction equation
Cl.[C:2]1([C:8]2[C:12]3=[C:13]([NH:17][CH2:18][CH:19]4[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]4)[N:14]=[N:15][CH:16]=[C:11]3[O:10][N:9]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:25]1([C:31]2[CH:35]=[C:34]([CH:36]=O)[O:33][N:32]=2)[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[C:2]1([C:8]2[C:12]3=[C:13]([NH:17][CH2:18][CH:19]4[CH2:24][CH2:23][N:22]([CH2:36][C:34]5[O:33][N:32]=[C:31]([C:25]6[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=6)[CH:35]=5)[CH2:21][CH2:20]4)[N:14]=[N:15][CH:16]=[C:11]3[O:10][N:9]=2)[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 113672673-Phenyl-1,2-oxazole-5-carbaldehydeHCID 66989956HCID 66989956, compound

Product 1

HCID 58504144HCID 58504144, compound

Procedure

According to the same procedure described in Example 35, using the compound obtained in Example 84 instead of the compound obtained in Example 11 and the aldehyde obtained in Example 7 instead of 4-phenylthiophene-2-carbaldehyde, the title compound having the following physical data was obtained.

Sources & evidence

ORD record
ord-72a31b8caf51498d847d408519326e65
Source dataset
uspto-grants-2014_08
Patent number
US08809538B2

Reaction notes

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