3-(4-Chlorophenyl)-1,2-oxazole-5-carbaldehyde → HCID 58504251, compound

HRID 2407691Notes

Reaction equation

HRID 2407691 reaction equation
Cl.[C:2]1([C:8]2[C:12]3=[C:13]([NH:17][CH2:18][CH:19]4[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]4)[N:14]=[N:15][CH:16]=[C:11]3[O:10][N:9]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:25][C:26]1[CH:31]=[CH:30][C:29]([C:32]2[CH:36]=[C:35]([CH:37]=O)[O:34][N:33]=2)=[CH:28][CH:27]=1>>[Cl:25][C:26]1[CH:27]=[CH:28][C:29]([C:32]2[CH:36]=[C:35]([CH2:37][N:22]3[CH2:23][CH2:24][CH:19]([CH2:18][NH:17][C:13]4[N:14]=[N:15][CH:16]=[C:11]5[O:10][N:9]=[C:8]([C:2]6[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=6)[C:12]=45)[CH2:20][CH2:21]3)[O:34][N:33]=2)=[CH:30][CH:31]=1

Participants

3

Reactant 2

HCID 143736013-(4-Chlorophenyl)-1,2-oxazole-5-carbaldehydeHCID 66989956HCID 66989956, compound

Product 1

HCID 58504251HCID 58504251, compound

Procedure

According to the same procedure described in Example 35, using the compound obtained in Example 84 instead of the compound obtained in Example 11 and 3-(4-chlorophenyl)isoxazole-5-carbaldehyde instead of 4-phenylthiophene-2-carbaldehyde, the title compound having the following physical data was obtained.

Sources & evidence

ORD record
ord-e5e8b47c799f4e5bbdcd40f7c0bc2f0a
Source dataset
uspto-grants-2014_08
Patent number
US08809538B2

Reaction notes

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