Boron tribromide → HCID 58504238, compound

Participants

Reaction Conditions

Reaction Steps

The compound prepared in Example 147 (0.295 g) was dissolved in dichloromethane (7 mL) and cooled to 0° C. Tribromoborane (0.3 mL) was added slowly and the reaction was allowed to warm and then was stirred overnight. The reaction was quenched with ethyl acetate/sodium hydrogen carbonate aqueous solution and the organic phase was washed with brine, dried over magnesium sulfate and filtered. The solution was concentrated and purified by column chromatography using an eluant of 5% methanol/dichloromethane to provide the title compound (0.10 g) having the following physical data.

Provenance & Evidence