HCID 20474893, compound → HCID 58504163, compound

HRID 2407734Notes

Reaction equation

HRID 2407734 reaction equation
[NH2:1][C:2]1[S:6][C:5]([C:7]([OH:9])=O)=[C:4]([CH3:10])[C:3]=1[C:11]#[N:12].[C:13]1([C:19]2[CH:23]=[C:22]([CH2:24][N:25]3[CH2:30][CH2:29][CH:28]([CH2:31][NH2:32])[CH2:27][CH2:26]3)[O:21][N:20]=2)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[NH2:1][C:2]1[S:6][C:5]([C:7]([NH:32][CH2:31][CH:28]2[CH2:27][CH2:26][N:25]([CH2:24][C:22]3[O:21][N:20]=[C:19]([C:13]4[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=4)[CH:23]=3)[CH2:30][CH2:29]2)=[O:9])=[C:4]([CH3:10])[C:3]=1[C:11]#[N:12]

Participants

3

Reactant 2

HCID 20474893HCID 20474893, compoundHCID 58504252HCID 58504252, compound

Product 1

HCID 58504163HCID 58504163, compound

Procedure

According to the same procedure described in Example 225, using the compound prepared in Example 227 instead of 4-amino-5-cyano-6-ethoxypicolinic acid, and using the compound prepared in Example 9 instead of tert-butyl 4-(aminomethyl)piperidine-1-carboxylate, the title compound having the following physical data was obtained.

Sources & evidence

ORD record
ord-655448dd472c49b7b22fd2c276505b99
Source dataset
uspto-grants-2014_08
Patent number
US08809538B2

Reaction notes

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