1083317-25-2 → HCID 66989148, compound

HRID 2407756Notes

Reaction equation

HRID 2407756 reaction equation
[NH2:1][C:2]1[C:7]([C:8]#[N:9])=[C:6]([O:10][CH2:11][CH3:12])[N:5]=[C:4]([C:13]([NH:15][CH2:16][C:17]2([O:23][CH3:24])[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]2)=[O:14])[CH:3]=1.[N:25]1[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=1[C:31]1[S:32][C:33]([CH:36]=O)=[CH:34][N:35]=1>>[NH2:1][C:2]1[C:7]([C:8]#[N:9])=[C:6]([O:10][CH2:11][CH3:12])[N:5]=[C:4]([C:13]([NH:15][CH2:16][C:17]2([O:23][CH3:24])[CH2:18][CH2:19][N:20]([CH2:36][C:33]3[S:32][C:31]([C:26]4[CH:27]=[CH:28][CH:29]=[CH:30][N:25]=4)=[N:35][CH:34]=3)[CH2:21][CH2:22]2)=[O:14])[CH:3]=1

Participants

3

Reactant 2

HCID 534037721083317-25-2HCID 66990903HCID 66990903, compound

Product 1

HCID 66989148HCID 66989148, compound

Procedure

According to the same procedure described in Example 101, starting with the compound prepared in Example 260 instead of the compound prepared in Example 226 and the compound prepared in Example 139 instead of 2-phenylthiazole-5-carbaldehyde, the title compound having the following physical data was obtained.

Sources & evidence

ORD record
ord-a68be4b4052347da8df2087040ef7179
Source dataset
uspto-grants-2014_08
Patent number
US08809538B2

Reaction notes

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