Aniline → HCID 5712530, compound

Participants

Reaction Steps

To a solution of dimethyl but-2-ynedioate (1.452 mL) in methanol (20 mL) was added aniline (0.98 mL) at room temperature. The mixture was stirred at room temperature overnight. The mixture was purified by column chromatography on silica gel (20-50% ethyl acetate in hexane) to obtain the title compound (1.73 g) having the following physical data.

Provenance & Evidence