HCID 58503948, compound → HCID 86659061, compound

HRID 2407771Notes

Reaction equation

HRID 2407771 reaction equation
[NH2:1][C:2]1[C:3]([Cl:14])=[N:4][C:5]([O:11][CH2:12][CH3:13])=[C:6]([CH:10]=1)[C:7]([OH:9])=O.[C:15]1([C:21]2[CH:25]=[C:24]([CH2:26][N:27]3[CH2:32][CH2:31][CH:30]([CH2:33][NH2:34])[CH2:29][CH2:28]3)[O:23][N:22]=2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[NH2:1][C:2]1[C:3]([Cl:14])=[N:4][C:5]([O:11][CH2:12][CH3:13])=[C:6]([CH:10]=1)[C:7]([NH:34][CH2:33][CH:30]1[CH2:29][CH2:28][N:27]([CH2:26][C:24]2[O:23][N:22]=[C:21]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH:25]=2)[CH2:32][CH2:31]1)=[O:9]

Participants

3

Reactant 2

HCID 58503948HCID 58503948, compoundHCID 58504252HCID 58504252, compound

Product 1

HCID 86659061HCID 86659061, compound

Procedure

According to the same procedure described in example 225, using the compound prepared in Example 292 instead of 4-amino-5-cyano-6-ethoxypicolinic acid, and using the compound prepared in Example 9 instead of tert-butyl 4-(aminomethyl)piperidine-1-carboxylate, the title compound having the following physical data was obtained.

Sources & evidence

ORD record
ord-c7c6aae6a23446729c426efdfd3b9de1
Source dataset
uspto-grants-2014_08
Patent number
US08809538B2

Reaction notes

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