Iodoethane → HCID 66989322, compound

Participants

Reaction Steps

A suspension of the compound prepared in Example 294 (1.75 g) and cesium carbonate (2.70 g) in N,N-dimethylformamide (21 mL) was stirred at room temperature for 2 hours. Ethyl iodide (0.663 mL) was added and stirring continued at room temperature for 18 hours. The solvent was evaporated in vacuo and the residue partitioned between a saturated aqueous solution of sodium bicarbonate and ethyl acetate. The combined organic extracts were washed with brine, dried and evaporated in vacuo to a yellow oil and purified by column chromatography on silica gel (10-50% ethyl acetate in hexane) to obtain the title compound (1.6 g) having the following physical data.

Provenance & Evidence