HCID 58504195, compound → HCID 66989398, compound

HRID 2407774Notes

Reaction equation

HRID 2407774 reaction equation
[NH2:1][C:2]1[C:3]([O:14][CH2:15][CH3:16])=[N:4][C:5]([O:11][CH2:12][CH3:13])=[C:6]([CH:10]=1)[C:7]([OH:9])=O.[C:17]1([C:23]2[CH:27]=[C:26]([CH2:28][N:29]3[CH2:34][CH2:33][CH:32]([CH2:35][NH2:36])[CH2:31][CH2:30]3)[O:25][N:24]=2)[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[NH2:1][C:2]1[C:3]([O:14][CH2:15][CH3:16])=[N:4][C:5]([O:11][CH2:12][CH3:13])=[C:6]([CH:10]=1)[C:7]([NH:36][CH2:35][CH:32]1[CH2:31][CH2:30][N:29]([CH2:28][C:26]2[O:25][N:24]=[C:23]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH:27]=2)[CH2:34][CH2:33]1)=[O:9]

Participants

3

Reactant 2

HCID 58504195HCID 58504195, compoundHCID 58504252HCID 58504252, compound

Product 1

HCID 66989398HCID 66989398, compound

Procedure

According to the same procedure described in Example 225, using the compound prepared in Example 298 instead of 4-amino-5-cyano-6-ethoxypicolinic acid, and using the compound prepared in Example 9 instead of tert-butyl 4-(aminomethyl)piperidine-1-carboxylate, the title compound having the following physical data was obtained.

Sources & evidence

ORD record
ord-84b2e6d8958f42fc8d904482d34e33c1
Source dataset
uspto-grants-2014_08
Patent number
US08809538B2

Reaction notes

Loading…