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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2407775Generated: October 31, 2026

4-Amino-5-cyano-6-ethoxypicolinic acid → HCID 66989271, compound

https://huagongshe.com/reaction/2407775

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Amino-5-cyano-6-ethoxypicolinic acidHCID 11846460—
ReactantHCID 58504252HCID 58504252—
ReactantHCID 66989402HCID 66989402—
ProductHCID 66989271HCID 66989271—

Reaction Steps

According to the same procedure described in example 225, using 4-amino-6-ethoxypicolinic acid (prepared according to the reported preparation in J. Med. Chem. 2006, 49(15), 4455-4458), instead of 4-amino-5-cyano-6-ethoxypicolinic acid, and the compound prepared in Example 9 instead of tert-butyl 4-(aminomethyl)piperidine-1-carboxylate, the title compound having the following physical data was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08809538B2
Source datasetuspto-grants-2014_08
ORD IDord-bcb52314b86f46fb8e2f1743941581f9
Source noteuspto-grants-2014_08