2-(Dimethylamino)ethanol → HCID 58503953, compound

Participants

Reaction Steps

A solution of the compound prepared in Example 303 (100 mg) in toluene (20 mL) was treated with oxalyl chloride (0.09 mL) for 2 hours at room temperature. 2-(dimethylamino)ethanol (873 mg) was added and the reaction was stirred for 1 hour at room temperature. The solution was diluted with ethyl acetate, washed with saturated aqueous sodium bicarbonate solution and brine. The organics were dried over magnesium sulfate, filtered and concentrated under reduced pressure to afford the title material (120 mg), which was used without further purification.

Provenance & Evidence