Trifluoroacetic acid → 4-phenoxy-N-(piperidin-4-ylmethyl)-1H-pyrazolo[4,3-c]pyridin-3-amine bis(2,2,2-trifluoroacetate)

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Reaction Steps

A solution of the compound prepared in Example 435 (0.262 g) in dichloromethane (3 mL) was treated with trifluoroacetic acid (0.6 mL) at room temperature. After stirring at room temperature for 4 hours, the mixture was shaken in dichloromethane and washed with aqueous saturated sodium bicarbonate, dried, and evaporated in vacuo to provide the title compound (0.065 g) with the following physical data.

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