HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2407857Generated: October 27, 2026
Triethyl Phosphate → Diethyl 2-(2-(2-iodoethoxy)ethoxy)ethylphosphonate
https://huagongshe.com/reaction/2407857
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethyl Phosphate | HCID 6535 | — |
| Reactant | 1,2-Bis(2-iodoethoxy)ethane | HCID 593436 | — |
| Product | Diethyl 2-(2-(2-iodoethoxy)ethoxy)ethylphosphonate | HCID 86667775 | — |
Reaction Steps
1,2-bis(2-iodoethoxy)ethane (1.0 eq) was mixed with triethyl phosphate (1 eq) then heated to 160° C. for 20 minutes by microwave. The crude mixture was purified by flash chromatography on a COMBIFLASH® system (ISCO) using 85-100% EtOAc/Hex to give diethyl 2-(2-(2-iodoethoxy)ethoxy)ethylphosphonate as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08808703B2 |
|---|
| Source dataset | uspto-grants-2014_08 |
|---|
| ORD ID | ord-f49bb6897e8b453eb5063671fcdb3aec |
|---|
| Source note | uspto-grants-2014_08 |
|---|
