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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 240845Generated: October 30, 2026

4,6-Dichloropyrimidine → 3-bromo-1-(6-chloropyrimidin-4-yl)-6-(4-methoxyphenyl)-1H-indole

https://huagongshe.com/reaction/240845

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4,6-DichloropyrimidineHCID 70943—
Reactant3-bromo-6-(4-methoxyphenyl)-1H-indoleHCID 66955054—
Product3-bromo-1-(6-chloropyrimidin-4-yl)-6-(4-methoxyphenyl)-1H-indoleHCID 50991546—

Reaction Steps

The target compound was prepared as in Example 9 using 3-bromo-6-(4-methoxyphenyl)-1H-indole (500 mg, 1.65 mmol) and 4,6-dichloropyrimidine (247 mg, 1.65 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08648089B2
Source datasetuspto-grants-2014_02
ORD IDord-b1b7a5deb60d466b8e92e6979ac99660
Source noteuspto-grants-2014_02