HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → 1-(4-Amino-3-bromo-phenyl)-cyclohexane carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 1-(4-Aminophenyl)cyclohexanecarbonitrile | HCID 49874526 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-(4-Amino-3-bromo-phenyl)-cyclohexane carbonitrile | HCID 58993760 | — |
Reaction Steps
The title compound was prepared from 1-(4-amino-phenyl)-cyclohexane carbonitrile (as prepared in the previous step) by bromination with NBS according to the procedure in Example 4, step (b), replacing CH3CN with CH2Cl2. 1H-NMR (CDCl3; 400 MHz): δ 7.49 (d, 1H, J=2.0 Hz), 7.23 (dd, 1H, J=8.4, 2.0 Hz), 6.76 (d, 1H, J=8.4 Hz), 2.16-2.08 (m, 2H), 1.90-1.73 (m, 8H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08815867B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-bb7316981032420e8788f85fe663082c |
| Source note | uspto-grants-2014_08 |