Boron tribromide → HCID 50991730, compound

HRID 240854Notes

Reaction equation

C[O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:17]3[C:12](=[CH:13][C:14]([C:18]4[CH:23]=[CH:22][CH:21]=[C:20]([N+:24]([O-:26])=[O:25])[CH:19]=4)=[CH:15][CH:16]=3)[N:11]([C:27]3[CH:32]=[CH:31][N:30]=[CH:29][CH:28]=3)[CH:10]=2)=[CH:5][CH:4]=1.B(Br)(Br)Br>>[N+:24]([C:20]1[CH:19]=[C:18]([C:14]2[CH:13]=[C:12]3[C:17]([C:9]([C:6]4[CH:7]=[CH:8][C:3]([OH:2])=[CH:4][CH:5]=4)=[CH:10][N:11]3[C:27]3[CH:28]=[CH:29][N:30]=[CH:31][CH:32]=3)=[CH:16][CH:15]=2)[CH:23]=[CH:22][CH:21]=1)([O-:26])=[O:25]

Participants

Reactant 2

HCID 25134Boron tribromide

HCID 50991729HCID 50991729, compound

Product 1

HCID 50991730HCID 50991730, compound

Procedure

The target compound was prepared as in Example 15 using 3-(4-methoxyphenyl)-6-(3-nitrophenyl)-1-(pyridin-4-yl)-1H-indole (58 mg, 0.138 mmol) and boron tribromide (BBr3, 65 μL, 0.691 mmol).

Sources & evidence

ORD record: ord-e56e0625c9ad40d7b6acebb9208c0edc
Source dataset: uspto-grants-2014_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08648089B2

Reaction notes

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