HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-chloro-5-(difluoroMethoxy)pyridine → HCID 86720121, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-chloro-5-(difluoroMethoxy)pyridine | HCID 50989408 | — |
| Reactant | [(S)-6-((R)-7-Fluoro-4-hydroxyindan-1-yloxy)-2,3-dihydrobenzofuran-3-yl]-acetic acid methyl ester | HCID 86720104 | — |
| Product | HCID 86720121 | HCID 86720121 | — |
Reaction Steps
The title compound is prepared from {(S)-6-[(R)-7-fluoro-4-hydroxy-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester and 5-difluoromethoxy-2-chloro-pyridine following a procedure analogous to that described for Intermediate 12. LC (method 2): tR=1.18 min; Mass spectrum (ESI+): m/z=502 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08815864B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-a724fac0e85145e4b942d71adde06365 |
| Source note | uspto-grants-2014_08 |