5-Hydroxy-2-methylbenzoxazole → {(S)-6-[(R)-7-Fluoro-4-(2-methyl-benzoxazol-5-yloxy)-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester

Participants

Reaction Steps

The title compound is prepared from (R)-7-fluoro-1-[(S)-3-methoxycarbonylmethyl-2,3-dihydrobenzofuran-6-yloxy]-2,3-dihydro-1H-inden-4-ylboronic acid and 5-hydroxy-2-methyl-benzoxazole following a procedure analogous to that described for Intermediate 6. LC (method 10): tR=0.85 min; Mass spectrum (ESI+): m/z=490 [M+H]+.

Provenance & Evidence