(2-Methyl-1,3-benzothiazol-6-yl)boronic acid → HCID 86720147, compound

Participants

Reaction Steps

The title compound is prepared from {(S)-6-[(R)-7-fluoro-4-hydroxy-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester and 2-methyl-benzothiazol-6-boronic acid (prepared from 2-methyl-benzothiazole-6-ylboronic acid pinacol ester using NaIO4 and NH4O2CCH3 in acetone and water) following a procedure analogous to that described for Intermediate 6. LC (method 3): tR=0.74 min; Mass spectrum (ESI+): m/z=506 [m+H]+.

Provenance & Evidence