3-Methylbenzo[d]isoxazol-5-ol → {(S)-6-[(R)-7-Fluoro-4-(3-methyl-benzo[d]isoxazol-5-yloxy)-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester

Participants

Reaction Steps

The title compound is prepared from (R)-7-fluoro-1-[(S)-3-methoxycarbonylmethyl-2,3-dihydrobenzofuran-6-yloxy]-2,3-dihydro-1H-inden-4-ylboronic acid and 3-methyl-benzo[d]isoxazol-5-ol following a procedure analogous to that described for Intermediate 6. LC (method 3): tR=0.68 min; Mass spectrum (ESI+): m/z=490 [M+H]+.

Provenance & Evidence