4-Fluoro-3-methylbenzonitrile → HCID 86720151, compound

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Reaction Steps

The methyl ester of the title compound is prepared from {(S)-6-[(R)-7-fluoro-4-hydroxy-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester and 4-fluoro-3-methyl-benzonitrile following a procedure analogous to that described for Intermediate 12. The title compound is obtained after saponification of the methyl ester as described for Example 1. LC (method 2): tR=1.14 min; Mass spectrum (ESI+): m/z=460 [M+H]+.

Provenance & Evidence