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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2408585Generated: November 2, 2026

[(S)-6-((R)-7-Fluoro-4-hydroxyindan-1-yloxy)-2,3-dihydrobenzofuran-3-yl]-acetic acid methyl ester → HCID 86720155, compound

https://huagongshe.com/reaction/2408585

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[(S)-6-((R)-7-Fluoro-4-hydroxyindan-1-yloxy)-2,3-dihydrobenzofuran-3-yl]-acetic acid methyl esterHCID 86720104—
ReactantHCID 86720156HCID 86720156—
ProductHCID 86720155HCID 86720155—

Reaction Steps

The methyl ester of the title compound is prepared from {(S)-6-[(R)-7-fluoro-4-hydroxy-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester and 2-dimethylamino-pyridineboronic acid following a procedure analogous to that described for Intermediate 6. The title compound is obtained after saponification of the methyl ester as described for Example 1. LC (method 2): tR=0.91 min; Mass spectrum (ESI+): m/z=465 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08815864B2
Source datasetuspto-grants-2014_08
ORD IDord-1054760ac25e4e2e851e0246d846d4ba
Source noteuspto-grants-2014_08