HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 3-Chloro-3-phenyl-2-propenenitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Acetophenone | HCID 7410 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Product | 3-Chloro-3-phenyl-2-propenenitrile | HCID 2777511 | 53% |
Reaction Steps
The reaction of dimethylformamide, phosphorous oxychloride and acetophenone as described earlier gave the product as an oil (0.72 g, 53%). 1H NMR (400 MHz, CDCl3): δ 7.64-7.67 (2H, m), 7.43-7.53 (3H, m), 6.02 (1H, s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08815879B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-30c8233de55c4d9083a42482ce25a0e8 |
| Source note | uspto-grants-2014_08 |