HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Chloro-2-(Methylsulfanyl)-[1,3]thiazolo[4,5-d]pyriMidine → HCID 86698301, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Chloro-2-(Methylsulfanyl)-[1,3]thiazolo[4,5-d]pyriMidine | HCID 14359388 | — |
| Reactant | 3-Amino-5-tert-butylselenophene-2-carboxamide | HCID 86646889 | — |
| Reactant | DMF NaOH | HCID 86698281 | — |
| Product | HCID 86698301 | HCID 86698301 | — |
Reaction Steps
The reaction of 7-chloro-2-(methylthio)thiazolo[4,5-d]pyrimidine with 3-amino-5-tert-butylselenophene-2-carboxamide in the presence of DMF/NaOH as described in Example 1 gave title compound as a pale color solid, mp 280-282° C. 1H NMR (400 MHz, DMSO-d6): δ 12.16 (1H, br s, exchangeable with D2O), 8.77 (1H, s), 8.15 (1H, s), 7.61 (2H, br s, exchangeable with D2O), 2.69 (3H, s), 1.39 (9H, s); LC-MS (positive ion mode): m/z 426, 428 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08815879B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-83313affdb4b4d2ebc210623effcd44c |
| Source note | uspto-grants-2014_08 |