m-Chloroperbenzoic acid → HCID 86689852, compound

Participants

Reaction Steps

To a solution of 6-fluoro-1-tosyl-1H-pyrrolo[3,2-b]pyridine (18 g, 62 mmol) in DCM (300 mL) was added MCPBA (16 g, 93 mmol). The mixture was stirred at RT overnight and then concentrated under reduced pressure. The residue was purified by SiO2 chromatography eluting with DCM:MeOH (30:1) to afford 23 g (100%) of 6-fluoro-1-tosyl-1H-pyrrolo[3,2-b]pyridine 4-oxide as a solid. MS (ESI) m/z: 307.1 [M+1]+.

Provenance & Evidence