HRID2409130

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2782838

1-(Trifluoromethyl)cyclobutanecarboxylic acid

C6H7F3O2

结构：CN1C(=O)C(C)(C)[C@@](C)(c2cc(N)ccc2F)N=C1NC(=O)OC(C)(C)C

HCID57496584

未命名化合物

2 次

PRODUCTS

生成物

结构：CN1C(=O)C(C)(C)[C@@](C)(c2cc(NC(=O)C3(C(F)(F)F)CCC3)ccc2F)N=C1N

HCID57516130

未命名化合物

PROCEDURE

实验过程

The coupling of [(S)-4-(5-amino-2-fluoro-phenyl)-1,4,5,5-tetramethyl-6-oxo-1,4,5,6-tetrahydro-pyrimidin-2-yl]-carbamic acid tert-butyl ester (intermediate F2) and 1-trifluoromethyl-cyclobutanecarboxylic acid followed by deprotection of the intermediate yielded the title compound as a white solid. MS (ESI): m/z=429.3 [M+H]+.