HRID2409133

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID385606

2H-Perfluoroisobutyric acid

C4H2F6O2

结构：CN1C(=O)C(C)(C)[C@@](C)(c2cc(N)ccc2F)N=C1NC(=O)OC(C)(C)C

HCID57496584

未命名化合物

2 次

PRODUCTS

生成物

结构：CN1C(=O)C(C)(C)[C@@](C)(c2cc(NC(=O)C(C(F)(F)F)C(F)(F)F)ccc2F)N=C1N

HCID86661860

未命名化合物

PROCEDURE

实验过程

The coupling of [(S)-4-(5-amino-2-fluoro-phenyl)-1,4,5,5-tetramethyl-6-oxo-1,4,5,6-tetrahydro-pyrimidin-2-yl]-carbamic acid tert-butyl ester (intermediate F2) and 3,3,3-trifluoro-2-trifluoromethyl-propionic acid followed by deprotection of the intermediate yielded the title compound as a white solid. MS (ESI): m/z=457.3 [M+H]+.