HRID2409137

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2778306

1-(Trifluoromethyl)cyclopropane-1-carboxylic acid

C5H5F3O2

结构：CC[C@H]1C(=O)N(C)C(NC(=O)OC(C)(C)C)=N[C@]1(C)c1cccc(N)c1

HCID57496604

未命名化合物

PRODUCTS

生成物

结构：CC[C@H]1C(=O)N(C)C(N)=N[C@]1(C)c1cccc(NC(=O)C2(C(F)(F)F)CC2)c1

HCID57516118

未命名化合物

PROCEDURE

实验过程

The coupling of give [(4S,5R)-4-(3-amino-phenyl)-5-ethyl-1,4-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyrimidin-2-yl]-carbamic acid tert-butyl ester and 1-trifluoromethyl-cyclopropanecarboxylic acid followed by deprotection of the intermediate yielded the title compound as a white solid. MS (ESI): m/z=397.2 [M+H]+.