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HRID2409145

反应详情

EQUATION

反应方程式

HRID 2409145 的结构方程式

REACTANTS

反应物

2
结构：COC(F)(C(=O)O)C(F)(F)F
HCID11105885

2,3,3,3-Tetrafluoro-2-methoxypropanoic acid

C4H4F4O3

结构：CN1C(=O)C(C)(C)[C@@](C)(c2cc(N)ccc2F)N=C1NC(=O)OC(C)(C)C
HCID57496584

未命名化合物

2 次

PRODUCTS

生成物

1
结构：COC(F)(C(=O)Nc1ccc(F)c([C@@]2(C)N=C(N)N(C)C(=O)C2(C)C)c1)C(F)(F)F
HCID57516129

未命名化合物

PROCEDURE

实验过程

The coupling of [(S)-4-(5-amino-2-fluoro-phenyl)-1,4,5,5-tetramethyl-6-oxo-1,4,5,6-tetrahydro-pyrimidin-2-yl]-carbamic acid tert-butyl ester (intermediate F2) and rac-2,3,3,3-tetrafluoro-2-methoxy-propionic acid followed by deprotection of the intermediate yielded the title compound as a colorless amorphous solid. MS (ESI): m/z=437.1 [M+H]+.