huagongshe.com
HRID2409156

反应详情

EQUATION

反应方程式

HRID 2409156 的结构方程式

REACTANTS

反应物

3
结构：CC(=O)C(F)(F)F
HCID9871

Trifluoroacetone

C3H3F3O

结构：CN1C(=O)C(C)(C)[C@@](C)(c2cc(N)ccc2F)N=C1N
HCID57497157

未命名化合物

2 次

结构：[B][B][B][B][B][B][B][B][B][B]
HCID178419135

未命名化合物

PRODUCTS

生成物

1
结构：CC(Nc1ccc(F)c([C@@]2(C)N=C(N)N(C)C(=O)C2(C)C)c1)C(F)(F)F
HCID57497051

未命名化合物

PROCEDURE

实验过程

The reductive amination of (S)-2-amino-6-(5-amino-2-fluoro-phenyl)-3,5,5,6-tetramethyl-5,6-dihydro-3H-pyrimidin-4-one (intermediate J) and 1,1,1-trifluoro-propan-2-one using decaborane yielded a mixture of epimers of the title compound as a white foam. MS (ESI): m/z=375.3 [M+H]+.

WORKUP

后处理

  1. customyielded